Review of new dietary supplements in the market

Review of new dietary supplements in the market: detailed analysis and assessment

I. Cognitive amplifiers (nootropics) of a new generation

1. N-phenylpropanoilaglitsin (NFPG) and its analogues:

   • The mechanism of action: NFPG, a synthetic analogue of endogenous neuropeptide, modulates NMDA receptors, potentiating long-term potential (LTP), a key mechanism of training and memory. Unlike classic nootropes, NFPG has a more selective effect, minimizing side effects associated with excessive stimulation of the nervous system. Analogs, such as phenylpiracetams (Phenotropil), have additional antioxidant and anticonvulsant properties. New developments are aimed at increasing bioavailability and prolonging the action of NFPG-like compounds by modifying the molecular structure and using delivery systems, such as liposomes and nanoparticles.
   • Clinical research: Preliminary clinical studies show the effectiveness of NFPG and its analogues in improving cognitive functions in patients with moderate cognitive impairment, Alzheimer’s disease (in the early stages) and after strokes. However, more large -scale and controlled research is necessary to confirm these results and determine the optimal dosages and application modes. Particular attention is paid to the study of the influence of NFPG on creativity and motivation, as well as its potential as adjuvant therapy in depression and anxiety disorders.
   • Side effects and contraindications: Headaches, irritability, insomnia and an increase in blood pressure are possible. Contraindicated during pregnancy, lactation, serious diseases of the liver and kidneys, as well as with individual intolerance. Caution should be observed with simultaneous use with other psychoactive substances. New formulas containing lower doses of NFPG in combination with other nootropic components (for example, holin, Bakopa Monieri) are aimed at reducing the risk of side effects and increasing overall effectiveness.
   • Market trends: The demand for NFPG and its analogues is growing, especially among students, professionals requiring high cognitive performance, and elderly people seeking to maintain clarity of the mind. Manufacturers are actively developing new forms of release (for example, sublingual tablets, nasal sprays) and combined products containing NFPG in combination with other useful substances. It is important to pay attention to the quality and authenticity of products, since fakes are found on the market.

2. Selective Sigma-1 receptor modulators (S1RMS):

   • The mechanism of action: Sigma-1 receptors (σ1r) play an important role in the modulation of neurotransmissia, neuroplasticity and survival of neurons. S1RMS, such as Permenhenolon and aniracetes, activate σ1R, which leads to an increase in synaptic transmission, increasing the level of the neurotrophic factor of the brain (BDNF) and protecting neurons from oxidative stress and exaytotoxicity. New S1RMS are developed taking into account greater selectivity and affinity to σ1R, as well as with an improved ability to penetrate through a hematoencephalic barrier.
   • Clinical research: Clinical studies show the potential effectiveness of the S1RMS in the treatment of cognitive disorders in Alzheimer’s disease, depression, schizophrenia and other neuropsychiatric disorders. S1RMS can improve memory, attention, concentration and mood, as well as reduce anxiety and depressive symptoms. However, further research is needed to determine optimal therapeutic strategies and identify patients of patients who most likely respond to treatment. The use of S1RMS as adjuvant therapy is also investigated to enhance the effect of antidepressants and other drugs.
   • Side effects and contraindications: Side effects are usually insignificant and include headache, dizziness, nausea and insomnia. Contraindicated during pregnancy, lactation, serious diseases of the liver and kidneys, as well as with individual intolerance. Caution should be observed with simultaneous use with other psychoactive substances. New studies are aimed at studying the long -term safety and efficiency of S1RMS.
   • Market trends: Interest in S1RMS is growing as promising cognitive amplifiers and means to improve mental health. Manufacturers are actively developing new drugs containing S1RMS in various forms of release and combinations with other nootropic components. It is important to pay attention to the quality and safety of products, as well as consult a doctor before starting.

3. Peptide noothropes (Selank, Noopepts and so analogy):

   • The mechanism of action: Peptide nootropics are short amino acid chains that affect the nervous system, modulating neurotransmissia, neuroplasticity and immune processes. Selank, an analogue of the endogenous peptide of the tuftsin, has anxiolytic and nootropic effects. Noopept, ethyl ether of dipeptide n-phenylacetile-l-prolilicin, improves cognitive functions, memory and attention. New peptide nootropics are developed taking into account greater bioavailability, stability and selectivity of action.
   • Clinical research: Clinical studies show the effectiveness of peptide nootropics in improving cognitive functions, reducing anxiety and depression, as well as increasing stress resistance. Selank is used to treat anxiety disorders and adapt to stress situations. Noopept is used to improve memory and attention in patients with cognitive disorders. Further research is aimed at studying the use of peptide nootropics in Alzheimer’s disease, Parkinson’s disease and other neurodegenerative diseases.
   • Side effects and contraindications: Side effects are usually insignificant and include drowsiness, headache and allergic reactions. Contraindicated during pregnancy, lactation, serious diseases of the liver and kidneys, as well as with individual intolerance. Caution should be observed with simultaneous use with other psychoactive substances. New studies are aimed at studying long -term safety and the effectiveness of peptide nootropics.
   • Market trends: The popularity of peptide nootropes is growing as relatively safe and effective means to improve cognitive functions and mental health. Manufacturers are actively developing new drugs containing peptide nootropes in various forms of release (for example, nasal sprays, injections, tablets) and combinations with other useful substances. It is important to pay attention to the quality and safety of products, as well as consult a doctor before starting.

II. New generation adaptogens

1. Mushroom extracts (lion’s mane, cordyceps, reishi):

   • The mechanism of action: Mushroom extracts have adaptogenic properties, that is, they contribute to increasing the body’s resistance to stress, improving immunity and normalizing physiological functions. The lion’s mane (Hericium Erinaceus) stimulates the growth of nerve cells and improves cognitive functions. Cordyceps sinensis increases the energy level, improves endurance and has anti -inflammatory properties. Reishi (Ganoderma Lucidum) strengthens the immune system, reduces stress levels and improves sleep quality. New studies are aimed at the release and study of specific bioactive compounds from mushrooms with maximum effectiveness.
   • Clinical research: Clinical studies show the effectiveness of mushroom extracts in improving cognitive functions, reducing anxiety and depression, increasing immunity and improving the quality of life. The lion’s mane showed promising the results in improving memory and attention in patients with moderate cognitive disorders. Cordyceps improves sports results and reduces fatigue. Reishi helps to cope with stress and improve sleep. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include stomach disorder, allergic reactions and skin rashes. Contraindicated during pregnancy, lactation, autoimmune diseases and individual intolerance. Caution should be observed with simultaneous use with immunosuppressants and anticoagulants. New studies are aimed at studying the safety and effectiveness of mushroom extracts with prolonged use.
   • Market trends: The popularity of mushroom extracts as natural and safe means is growing to improve health and increase stress resistance. Manufacturers are actively developing new products containing mushroom extracts in various forms of release (for example, capsules, powders, teas) and combinations with other adaptogenic components. It is important to pay attention to the quality and authenticity of products, as well as choose products that have undergone quality control and contain standardized extracts.

2. Plant adaptogens (rhodiola pink, Ashvaganda, eleutherococcus):

   • The mechanism of action: Plant adaptogens, such as rhodiola pink (Rhodiola rosea), Ashvaganda (Withania somnifera) and eleutherococcus (Eleutherococcus senticosus), have the ability to increase the body’s stress resistance, improve physical and mental performance, and also normalize. immune function. Rhodiola pink improves energy level, improves mood and cognitive functions. Ashvaganda reduces stress and anxiety, improves sleep and strengthens the immune system. Eleutherococcus increases endurance, improves concentration and reduces fatigue. New studies are aimed at studying specific bioactive compounds in these plants and their mechanisms of action.
   • Clinical research: Clinical studies show the effectiveness of plant adaptogens in improving cognitive functions, reducing anxiety and depression, increasing physical performance and improving the quality of life. Rhodiola Pink showed promising the results in improving attention and memory among students during exams. Ashvaganda reduces the level of cortisol and improves sleep quality in people experiencing stress. Eleutherococcus increases endurance in athletes and reduces fatigue in people working in stress conditions. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include stomach disorder, headache and allergic reactions. Contraindicated during pregnancy, lactation, autoimmune diseases, hypertension and individual intolerance. Caution should be observed with simultaneous use with antidepressants, immunosuppressants and anticoagulants. New studies are aimed at studying the safety and efficiency of plant adaptogens with prolonged use.
   • Market trends: The demand for plant adaptogens is growing as natural and safe means to increase resistance to stress and improve the general state of health. Manufacturers are actively developing new products containing plant adaptogens in various forms of production (for example, capsules, tablets, powders, teas) and combinations with other useful substances. It is important to pay attention to the quality and authenticity of products, as well as choose products that have undergone quality control and contain standardized extracts.

3. Antioxidants (Astaxantin, Picnogenol, Resveratrol):

   • The mechanism of action: Antioxidants, such as astaxantin, pycnogenol and resveratrol, protect the body cells from damage by free radicals, which are formed as a result of oxidative stress. Oxidative stress plays an important role in the development of many chronic diseases, including cardiovascular diseases, cancer and neurodegenerative diseases. Astaxantin is a powerful antioxidant that protects cells from damage by ultraviolet radiation and improves vision. Picnogenol improves blood circulation, reduces inflammation and protects the skin from aging. Resveratrol activates sirtuins, proteins, which are involved in the regulation of cellular aging and metabolism. New studies are aimed at studying the specific mechanisms of the action of antioxidants and their influence on various aspects of health.
   • Clinical research: Clinical studies show the effectiveness of antioxidants in a decrease in the risk of developing chronic diseases, improving the health of the skin and improving the overall health. Astaxantin showed promising the results in improving vision, reducing inflammation and protecting the skin from sunburn. Picnogenol improves blood circulation, reduces blood pressure and improves skin elasticity. Resveratrol can protect against cardiovascular diseases, cancer and neurodegenerative diseases. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include stomach disorder, headache and allergic reactions. Contraindicated during pregnancy, lactation, autoimmune diseases and individual intolerance. Caution should be observed with simultaneous use with anticoagulants and anti -signs. New studies are aimed at studying the safety and effectiveness of antioxidants with prolonged use.
   • Market trends: The demand for antioxidants is growing as a means to protect against aging and the prevention of chronic diseases. Manufacturers are actively developing new products containing antioxidants in various forms of release (for example, capsules, tablets, creams, serums) and combinations with other beneficial substances. It is important to pay attention to the quality and authenticity of products, as well as choose products that have undergone quality control and contain standardized extracts.

III. Sleeping preparations

1. Melatonin of prolonged action:

   • The mechanism of action: Melatonin is a hormone regulating circus rhythms of sleep and wakefulness. Melatonin prolonged action ensures the gradual release of melatonin during the night, imitating the natural profile of the secretion of melatonin in the body. This helps to improve sleep quality, reduce falling asleep and reduce the number of night awakenings. New formulas of prolonged melatonin are developed taking into account greater bioavailability and stability.
   • Clinical research: Clinical studies show the effectiveness of a prolonged melatonin in the treatment of insomnia, especially in older people and people working in shifts. A prolonged melatonin improves sleep quality, reduces the time of falling asleep and reduces the number of night awakenings without side effects characteristic of sleeping pills. Further research is aimed at studying the use of prolonged melatonin with other sleep disorders, such as sleeping phase delay and sleep disturbances associated with travel (Jetlag).
   • Side effects and contraindications: Side effects are usually insignificant and include drowsiness, headache and dizziness. Contraindicated during pregnancy, lactation, autoimmune diseases and individual intolerance. Caution should be observed with simultaneous use with antidepressants, anticoagulants and sleeping pills. New studies are aimed at studying the safety and effectiveness of prolonged melatonin with prolonged use.
   • Market trends: The popularity of prolonged melatonin is growing as a safe and effective means to improve sleep. Manufacturers are actively developing new products containing prolonged melatonin in various dosages and forms of release (for example, tablets, capsules, candies). It is important to pay attention to the quality and authenticity of the product, as well as consult a doctor before starting.

2. Vegetable sleeping pills (Valerian, Hops, Melissa):

   • The mechanism of action: Vegetable sleeping pills, such as Valeriana Officinalis, Humulus Lupulus and Melissa (Melissa Officinalis), have soothing and sleeping pills. Valerian reduces nervous excitement, improves sleep quality and reduces the time of falling asleep. Hops have a sedative and anxiolytic effect. Melissa reduces anxiety, improves mood and promotes relaxation. New studies are aimed at studying the synergistic effect of plant sleeping pills.
   • Clinical research: Clinical studies show the effectiveness of plant sleeping pills in improving sleep quality and reducing anxiety. Combinations of Valerian, Hops and Melissa showed promising the results in the treatment of mild and moderate insomnia. Plant sleeping pills are usually well tolerated and do not cause side effects characteristic of synthetic sleeping pills. Further research is aimed at studying the use of plant sleeping pills for other sleep disorders, such as restless legs syndrome and sleep disturbances associated with stress.
   • Side effects and contraindications: Side effects are usually insignificant and include drowsiness, headache and stomach. Contraindicated during pregnancy, lactation and individual intolerance. Caution should be observed with simultaneous use with other sedatives and alcohol. New studies are aimed at studying the safety and efficiency of plant sleeping pills for prolonged use.
   • Market trends: The demand for plant sleeping pills is growing as natural and safe means to improve sleep. Manufacturers are actively developing new products containing plant sleeping pills in various forms of release (for example, tablets, capsules, teas, extracts) and combinations with other soothing components. It is important to pay attention to the quality and authenticity of products, as well as choose products that have undergone quality control and contain standardized extracts.

3. Magnesium L-Treonate:

   • The mechanism of action: Magnesium is an important mineral that is involved in many physiological processes, including sleep regulation. Magnesium L-treonata is a form of magnesium, which has an increased ability to penetrate through a hematoencephalic barrier and increase the level of magnesium in the brain. This can improve sleep quality, reduce anxiety and improve cognitive functions. New studies are aimed at studying the influence of magnesium of the L-treonat on neuroplasticity and synaptic function.
   • Clinical research: Clinical studies show the effectiveness of magnesium L-treonat in improving the quality of sleep, reducing anxiety and improving cognitive functions. Magnesium L-treonat can improve sleep in people who have stress and anxiety, as well as improve memory and attention in older people. Further research is aimed at studying the use of magnesium L-treonat with other disorders, such as depression and neurodegenerative diseases.
   • Side effects and contraindications: Side effects are usually insignificant and include stomach and diarrhea. It is contraindicated in severe renal failure and individual intolerance. Caution should be observed with simultaneous use with antibiotics and drugs containing calcium. New studies are aimed at studying the safety and efficiency of magnesium L-treonat with prolonged use.
   • Market trends: Interest in the magnesium of L-treonata as a promising tool for improving sleep, reduce anxiety and improve cognitive functions is growing. Manufacturers are actively developing new products containing L-treonat magnesium in various dosages and forms of release (for example, capsules, powders). It is important to pay attention to the quality and authenticity of the product, as well as consult a doctor before starting.

IV. Digestion improvement preparations

1. Postbiotics:

   • The mechanism of action: Postbiotics are bioactive compounds that are formed as a result of vitality in the intestines. They include short -chain fatty acids (KCHK), bacterial cell fragments, vitamins and other metabolites. Postbiotics have a direct effect on the intestines, improving its barrier function, reducing inflammation, stimulating the growth of beneficial bacteria and modulating the immune system. Unlike probiotics, postbiotics do not contain living microorganisms, which makes them more stable and safe for people with weakened immunity. New studies are aimed at studying the specific effects of various postbiotics and their impact on various aspects of health.
   • Clinical research: Clinical studies show the effectiveness of postbiotics in improving digestion, reducing inflammation in the intestines, improving immunity and preventing various diseases. KCZHK, such as butyrate, acetate and propionate, nourish the intestinal cells, improve its barrier function and reduce the risk of developing inflammatory diseases of the intestine. Postbiotics can also improve the symptoms of irritable intestines (SRK), reduce the risk of allergies and improve the general health. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include gas formation and bloating. Contraindicated in individual intolerance. Caution should be observed with simultaneous use with antibiotics. New studies are aimed at studying the safety and effectiveness of postbiotics with prolonged use.
   • Market trends: Interest in postbiotics is growing as promising means to improve digestion and maintain intestinal health. Manufacturers are actively developing new products containing postbiotics in various forms of release (for example, capsules, powders, drinks) and combinations with probiotics and prebiotics. It is important to pay attention to the quality and authenticity of products, as well as choose products containing standardized postbiotic extracts.

2. Digestive enzymes of a wide range of action:

   • The mechanism of action: Digestive enzymes, such as amylase, protease, lipase, cellulose and lactase, break down complex food molecules into simpler ones, which are easily absorbed by the body. The digestive enzymes of a wide spectrum of action contain a combination of various enzymes that help digest various types of food, including carbohydrates, proteins, fats and fiber. This can improve digestion, reduce bloating, gas formation and discomfort after eating. New digestive enzymes are developed taking into account greater stability and activity in various PH conditions.
   • Clinical research: Clinical studies show the effectiveness of digestive enzymes of a wide spectrum of action in improving digestion and reducing symptoms of dyspepsia. Digestive enzymes can help people with enzymes, such as lactose intolerance, digest lactose and reduce symptoms, such as bloating and diarrhea. They can also help people with irritable intestines (SRK) reduce symptoms, such as abdominal pain and bloating. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include nausea, diarrhea and allergic reactions. Contraindicated in individual intolerance. Caution should be observed with simultaneous use with anticoagulants. New studies are aimed at studying the safety and effectiveness of digestive enzymes with prolonged use.
   • Market trends: The demand for digestive enzymes of a wide spectrum of action is growing as a means to improve digestion and reduce discomfort after eating. Manufacturers are actively developing new products containing digestive enzymes in various forms of release (for example, capsules, tablets, powders) and combinations with probiotics and prebiotics. It is important to pay attention to the quality and authenticity of products, as well as choose products containing standardized enzymes.

3. Plant drugs to support the liver (silimarin, artichoke, turmeric):

   • The mechanism of action: Plant preparations for supporting the liver, such as silimarin (spotting extract), artichoke (Cynara Scolymus) and turmeric (Curcuma Longa), have hepatoprotective properties, that is, protect the liver from damage. Silimarin is a powerful antioxidant that protects the liver cells from damage to free radicals and improves its regeneration. The artichoke stimulates the production of bile and improves the detoxification of the liver. Turmeric has anti -inflammatory and antioxidant properties that protect the liver from damage. New studies are aimed at studying the specific mechanisms of the action of these plant drugs and their influence on various aspects of the liver health.
   • Clinical research: Clinical studies show the effectiveness of plant drugs to support the liver in improving the liver function and protecting it from damage. Silimarin showed promising the results in the treatment of liver diseases, such as hepatitis, cirrhosis and fatty hepatosis. The artichoke can improve the liver function and reduce cholesterol. Turmeric can protect the liver from damage caused by alcohol and toxins. Further research is needed to confirm these results and determine the optimal dosages and application modes.
   • Side effects and contraindications: Side effects are usually insignificant and include stomach disorder, diarrhea and allergic reactions. Contraindicated during pregnancy, lactation and individual intolerance. Caution should be observed with simultaneous use with anticoagulants and drugs metabolizing in the liver. New studies are aimed at studying the safety and efficiency of plant drugs to support the liver with prolonged use.
   • Market trends: Demand for plant drugs is growing to support the liver as a means to protect the liver from damage and improve its function. Manufacturers are actively developing new products containing these plant drugs in various forms of release (for example, capsules, tablets, powders) and combinations with other useful substances. It is important to pay attention to the quality and authenticity of products, as well as choose products that have undergone quality control and contain standardized extracts.

This detailed overview provides a comprehensive analysis of new dietary supplements in the market, covering cognitive enhancers, adaptogens, sleep aids, and digestive health products. It is structured for easy reading and provides detailed information on mechanisms of action, clinical studies, side effects, contraindications, and market trends for each category of supplements. The content is designed to be SEO-optimized with relevant keywords and phrases.