Revolutionary approach: we get rid of migraine once and for all

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Revolutionary approach: we get rid of migraine once and for all

Migraine is more than just a headache. This is an exhausting neurological disease that can paralyze for clocks, days, and sometimes weeks. It is characterized by an intense pulsating headache, often accompanied by nausea, vomiting, sensitivity to light (photophobia) and sound (phonophobia). Migraine can significantly affect the quality of life, interfering with work, study, social interactions and even everyday matters.

Despite the fact that migraine is a common disease that affects about 12% of the world’s population, many people do not receive adequate treatment or do not know about revolutionary approaches that can help them get rid of migraine once and for all. In this article, we will consider a comprehensive and multifaceted approach to the treatment of migraines, based on recent scientific research and clinical experience, to help you take control of your life and get rid of pain.

Chapter 1: Understanding the roots of migraine: more than just a headache

To effectively fight migraine, you need to understand its complex mechanisms. Migraine is not just a “headache”. This is a complex neurological process, including the interaction of genetic factors, the environment and changes in brain activity.

1.1. Genetic predisposition:

Migraine has a strong genetic component. If you have close relatives suffering from migraine, your chances of developing this disease increase significantly. Several genes were identified as related to migraine, including genes affecting the function of ion channels, neurotransmitters and blood vessels.

However, genetics is not the only factor. The presence of a genetic predisposition does not mean that you will definitely suffer from migraine. Environmental factors and lifestyle also play an important role in activation and manifestation of migraine attacks.

1.2. Migraine triggers:

Migraine triggers are factors that can provoke a migraine attack of predisposed people. Migraines triggers are individual and can vary from person to person. Some common triggers include:

  • Nutrition: Certain products and drinks, such as sustained cheeses, chocolate, red wine, processed meat, artificial sweeteners (aspartam), sodium glutamate (MSG) and caffeine (in abundance or with a sharp termination of use).
  • Stress: Physical, emotional or psychological stress is one of the most common migraine triggers.
  • Hormonal changes: In women, migraine is often associated with a menstrual cycle, pregnancy and menopause. Changes in estrogen levels can provoke migraine attacks.
  • Weather changes: Swanks of atmospheric pressure, humidity, temperature and strong wind.
  • Sleep disorders: lack of sleep, excessive sleep or a change in sleep mode.
  • Environment: Bright light, loud sounds, strong smells (perfume, smoke, chemicals) and flashing lights.
  • Physical activity: Excessive physical activity, especially in the heat.
  • Passing of food intake: A low blood sugar can provoke migraines.
  • Dehydration: The lack of fluid in the body.
  • Medicines: Some drugs, such as oral contraceptives, vasodilators and some antibiotics.

1.3. Migraine neurobiology:

Migraine is associated with changes in brain activity, especially in areas responsible for painting pain, sensory information and emotions. Key neurobiological processes involved in migraines include:

  • Activation of trigeminal nerve: The trigeminal nerve is a large nerve that is responsible for the transmission of sensory information from the face, head and neck to the brain. Activation of the trigeminal nerve leads to the release of neuropeptides, such as calcitonin-gen-tied peptide (CGRP), which plays a key role in the development of migraine.
  • Expansion of the vessels of the brain: It was believed that the expansion of the vessels of the brain is the main cause of migraine. However, modern studies show that vascular expansion is more a consequence than the cause of migraine.
  • Inflammation: Inflammation in the brain and around it plays an important role in the development and maintenance of migraines. Inflammatory molecules can sensitize pain receptors and aggravate headache.
  • Cortical depression (CSD): CSD is a slow wave of electrical activity, which spreads through the cerebral cortex and can cause an aura preceding migraines. CSD can also activate the trigeminal nerve and contribute to the development of headache.
  • Disruption of neurotransmitters: Neurotransmitters, such as serotonin, dopamine and norepinephrine, play an important role in the regulation of pain, mood and sleep. Violations in the work of these neurotransmitters can contribute to the development of migraines.

Chapter 2: A comprehensive approach to the treatment of migraines: more than just a tablet

Migraine treatment should be complex and take into account the individual characteristics of the patient, his triggers, the history of the disease and preferences. Simple acceptance of a tablet to relieve pain can bring temporary relief, but does not solve the main problem. The revolutionary approach to the treatment of migraine includes a combination of drugs and non -drug methods aimed at preventing attacks, relief of pain and improving the overall quality of life.

2.1. Keeping a headache diary:

Making a headache diary is an important first step in the treatment of migraine. In the diary you need to record:

  • The date and time of the beginning and end of the headache.
  • The intensity of pain (on a scale from 1 to 10).
  • Type of pain (pulsating, pressing, dumb, etc.).
  • Localization of pain (one side of the head, both sides, forehead, whiskey, etc.).
  • Related symptoms (nausea, vomiting, photophobia, phonophobia, aura, etc.).
  • Possible triggers (food, stress, weather changes, sleep disturbances, etc.).
  • Accepted drugs and their effectiveness.

Keeping a headache diary will help you and your doctor identify your individual triggers, evaluate the effectiveness of treatment and adjust the treatment plan.

2.2. Non -drug methods for treating migraines:

Non -drug migraine treatment methods are an important part of an integrated approach and can help reduce the frequency and intensity of seizures, as well as reduce the need for drugs.

  • Life change change:

    • Compliance with sleep mode: Try to go to bed and wake up at the same time every day, even on weekends.
    • Regular nutrition: Do not skip food meals and avoid long breaks between meals.
    • Sufficient fluid consumption: Drink enough water during the day.
    • Regular physical exercises: Regular physical activity, such as walking, swimming or cycling, can help reduce the frequency of migraines. Avoid excessive physical activity, especially in the heat.
    • Stress management: Learn to cope with stress with the help of techniques such as meditation, yoga, breathing exercises or tai-chi.
    • Restriction of alcohol and caffeine: Excessive consumption of alcohol and caffeine can provoke migraines.
    • Refusal of smoking: Smoking can increase the risk of migraine.

  • Biological feedback (BOS): Bos is a method that allows you to learn how to control physiological processes, such as heart rate, muscle tension and skin temperature. Bos can help reduce the frequency and intensity of migraines.

  • Acupuncture: Acupuncture is a traditional Chinese medical practice, which includes the introduction of thin needles into certain points on the body. Acupuncture can help reduce the frequency and intensity of migraines.

  • Massage: Massage can help relax the muscles of the neck and shoulders, reduce tension and reduce headache.

  • Cognitive-behavioral therapy (KPT): KPT is a type of psychotherapy that helps you change the negative thoughts and behavior associated with migraine. KPT can help you better cope with pain, anxiety and depression associated with migraine.

  • Relaxation techniques: Relaxation techniques, such as progressive muscle relaxation, autogenic training and visualization, can help reduce stress and stress that migraine can provoke.

  • Transcranial magnetic stimulation (TMS): TMS is a non -invasive method of brain stimulation that uses magnetic impulses to influence certain areas of the brain. TMS can be effective for the treatment of migraine with an aura.

  • Neurostimulation: Some neurostimulating devices, such as a trigeminal stimulator, can help reduce the frequency and intensity of migraines.

2.3. Migrant treatment of migraines:

Medication of migraine includes two main categories of drugs:

  • Preparations for stopping migraine attacks (abortive drugs): These drugs are taken in case of an attack of migraine to relieve pain and other symptoms.

    • Painkillers: Non -steroidal anti -inflammatory drugs (NSAIDs), such as Ibuprofen, Nenproxen and Diclofenac, can be effective for the treatment of lungs and moderate migraines.
    • TRIPTA: Triptans, such as summptor, risitriceptane, zolmitriptan, intrigratypan, frutitripphan, al -Recryptan and ethletriptan, are specific preparations for the treatment of migraine. They work, narrowing the blood vessels of the brain and blocking the release of neuropeptides, such as CGRP.
    • Dihydroergotamin (DGE): DGE is a drug that also narrows the blood vessels of the brain. DGE is available in the form of injections, nasal spray and tablets.
    • Gepant: Hyans, such as Rimehepant and Urogepant, are a new class of drugs for the treatment of migraine, which block the CGRP receptor. They are effective for the treatment of migraines with an aura and without aura.
    • Ditan: Ditans, such as lasmiditan, are another new class of drugs for the treatment of migraine, which affect serotonin receptors. They are effective for the treatment of migraines with an aura and without aura.

  • Migraine prevention drugs (preventive drugs): These drugs are taken daily to reduce the frequency and intensity of migraine attacks.

    • Beta blockers: Beta blockers, such as propranolol, metoprolol and atenolol, can help reduce the frequency of migraines.
    • Calcium channel blockers: Calcium channel blockers, such as fluanarisine and verapamil, can help reduce the frequency of migraines.
    • Antidepressants: Tricyclic antidepressants, such as amitriptylin, and selective inhibitors of the reverse capture of serotonin and norepinephrine (SIOSSN), such as Venlafaxin and Dululsetine, can help reduce the frequency of migraines.
    • Anticonvulsants: Anticonvulsants, such as valproic acid and topiramate, can help reduce the frequency of migraines.
    • Botox injections: Botox injections can be effective for the treatment of chronic migraines (migraine that occurs 15 or more days a month).
    • Monoclonal antibodies to CGRP: Monoclonal antibodies to CGRP, such as Erenumab, Freanzumab, Galkanzumab and Eptynesumab, are a new class of preventive drugs for the treatment of migraine, which block CGRP or its receptor. They are introduced in the form of injections once a month or once a quarter.

2.4. An individual approach to the treatment of migraines:

It is important to remember that there is no universal approach to the treatment of migraine. What works for one person may not work for another. Your doctor should develop an individual treatment plan that takes into account your specific symptoms, triggers, the history of the disease and preferences. It is important to openly communicate with your doctor and inform him of any changes in your symptoms or side effects of drugs.

Chapter 3: Revolutionary strategies for long -term control over migraine

In addition to traditional methods for treating migraines, there are revolutionary strategies that can help you achieve long -term control over this disease and get rid of migraine once and for all.

3.1. Neuroplasticity and renewal of the brain:

Neuroplasticity is the ability of the brain to change and adapt in response to experience. Using the principles of neuroplasticity, you can re -read the brain and reduce its susceptibility to migraine.

  • Brain training applications: There are brain training applications that are designed to improve cognitive functions, such as attention, memory and information processing speed. Some of these applications can also help reduce the frequency and intensity of migraines.
  • Neurofedbek: NeurofedBek is a type of BOS that uses electroencephalography (EEG) to monitor the activity of the brain and the provision of feedback in real time. Neurofedback can help you learn to regulate your brain activity and reduce the frequency of migraines.

3.2. Diet and food:

Diet and nutrition play an important role in the treatment of migraines. Certain products and drinks can provoke migraines, while others can help reduce its frequency and intensity.

  • Elimination diet: The elimination diet includes the exclusion of certain food products from your diet to identify your individual triggers. General products that are excluded from the elimination diet include:
    • Sustained cheeses
    • Chocolate
    • Red wine
    • Processed meat
    • Artificial sweeteners (aspartam)
    • Glutamate sodium (MSG)
    • Caffeine

After the exclusion of these products, for several weeks, they are gradually returned to the diet one by one to determine which of them provoke migraines.

  • Ketogenic diet: A ketogenic diet is a high fat diet, a moderate protein content and a low carbohydrate content. Ketogenic diet can help reduce the frequency of migraines in some people.
  • Supplements: Some additives can help reduce the frequency and intensity of migraines, including:
    • Magnesium: Magnesium plays an important role in the function of nerves and muscles. Magnesium deficiency can contribute to the development of migraine.
    • Riboflavin (vitamin B2): Riboflavin plays an important role in the production of energy in cells. Riboflavin can help reduce the frequency of migraines.
    • Coenzim q10: Coenzym Q10 plays an important role in the production of energy in cells. Coenzyme Q10 can help reduce the frequency of migraines.
    • Melatonin: Melatonin is a hormone that regulates the dream. Melatonin can help improve sleep and reduce the frequency of migraines.
    • COQ10 (Coanzim Q10): It has antioxidant properties and can improve energy metabolism in brain cells.

3.3. Attention to intestinal microbioma:

The intestinal microbia is a set of microorganisms that live in our intestines. More and more studies show that intestinal microbia can play an important role in the development and treatment of migraine.

  • Probiotics: Probiotics are living microorganisms that can bring health benefits when they are accepted in adequate quantities. Probiotics can help improve the composition of the intestinal microbioma and reduce the frequency of migraines.
  • Prebiotics: Prebiotics are undigested fibers that serve as food for beneficial bacteria in the intestines. Prebiotics can help improve the composition of the intestinal microbioma and reduce the frequency of migraines.
  • Transplantation of fecal microbiots (TFM): TFM is a procedure that includes the transfer of fecal microbiota from a healthy donor to the recipient. TFM can help restore a healthy intestinal microbia and reduce the frequency of migraines.

3.4. Integrative medicine:

Integrative medicine is an approach to treatment, which combines traditional methods of treatment with complementary and alternative methods such as acupuncture, massage, yoga and meditation. Integrative medicine can help reduce the frequency and intensity of migraines, improve the general quality of life and reduce the need for medicines.

Chapter 4: New horizons in the treatment of migraines: Innovative approaches

Science does not stand still, and new and innovative approaches to the treatment of migraines are constantly being developed.

4.1. Genoma therapy:

Genoma therapy is a promising direction in the treatment of migraine, which includes a change in the human genetic code to eliminate the cause of the disease. Genoma therapy is located in the early stages of development, but it can offer a potential solution for people suffering from severe and resistant migraine treatment.

4.2. Nanotechnology:

Nanotechnology is the use of materials and devices at Nanoural. Nanotechnologies can be used to develop new drugs for the treatment of migraine, as well as for the delivery of drugs directly to the brain.

4.3. Artificial intelligence (AI):

AI can be used to analyze large volumes of migraine data and identify new triggers and risk factors. AI can also be used to develop individual treatment plans that will be more effective for each person.

4.4. Virtual reality (VR):

VR can be used to create an immersive environment that will help reduce stress and stress associated with migraine. VR can also be used to teach relaxation and control techniques.

Chapter 5: Life without migraine: Strategies for maintaining brain health and relapse prevention

After achieving control over migraine, it is important to maintain brain health and take measures to prevent relapse.

5.1. Continuation of the head of the headache diary:

Continue to keep a headache diary to track your symptoms and identify possible triggers. This will help you respond quickly to any changes in your symptoms and prevent the development of a full -fledged migraine attack.

5.2. Compliance with a healthy lifestyle:

Observe a healthy lifestyle, including sleep mode, regular nutrition, sufficient fluid consumption, regular physical exercises and stress management.

5.3. Support for social ties:

Maintain social ties and spend time with friends and family. Social isolation can aggravate the symptoms of migraines.

5.4. Regular visits to the doctor:

Regularly visit your doctor to monitor your condition and adjust the treatment plan, if necessary.

5.5. Positive thinking:

Keep a positive attitude and believe in your ability to control your migraine. Positive thinking can help reduce stress and improve your overall well -being.

Migraine is a complex and exhausting disease, but with the help of a comprehensive and multifaceted approach to treatment, based on recent scientific research and clinical experience, you can take control of your life and get free from pain once and for all. Do not despair if you have tried many different methods of treatment, and nothing helped. Remember that science is constantly developing, and new and innovative approaches to the treatment of migraine are constantly being developed. Do not give up and continue to look for what works for you. With the support of a doctor, family and friends, as well as with faith in yourself, you can succeed and live a full life without migraine.

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