New dietary supplements in the market: review of the latest developments

Section 1: Innovation in Nutrician: Development Vector

The market of biologically active additives (BAD) is undergoing a period of rapid growth and transformation. In recent years, due to the in -depth understanding of molecular mechanisms underlying health and diseases, as well as the development of extraction, synthesis and delivery of active substances, many innovative products have appeared. The evolution of dietary supplements is moving in the direction of greater purposefulness, efficiency and safety. This is due to the growing demand from consumers who become more aware of the advantages of preventive medicine and strive to actively participate in maintaining their health.

1.1. Personalized nutrition and nutrigenomy:

One of the key trends is the personalization of the nutrition. This implies the development of dietary supplements, the composition of which takes into account individual genetic characteristics, metabolic profile and the needs of a particular person. Nutrigenomy, which studies the interaction between genes and nutrients, plays a central role here.

Genetic tests and dietary supplements: Companies offer genetic tests that analyze the polymorphisms of genes associated with the metabolism of vitamins, minerals, antioxidants and other important nutrients. Based on the results of such tests, individual recommendations are formed to receive dietary supplements to optimize the absorption of nutrients and reduce the risk of developing diseases. For example, people with certain options for the MthFR gene (methylentetrahydrofolateredustase) may need a methylated form of folic acid to maintain a normal level of homocysteine.
Microbimic profiling and probiotics of a new generation: Analysis of the intestinal microbioma allows you to identify the imbalance of microflora and determine the need for certain probiotics strains. Probiotics of a new generation containing prebiotic fibers are developed that support the growth of beneficial bacteria, as well as postbiotics – metabolites secreted by probiotics, which have a wide range of biological activity. An example is Akkermansia Muciniphila, a probiotic who showed promising results in improving metabolic health and weight control.
Metabolomics and individual selection of nutrients: Metabolomics is a study of the totality of all metabolites in the body. Analysis of metabolism allows you to identify deficits or excesses of certain substances and develop individual dietary supplement reception schemes to restore the metabolic balance. For example, an analysis of the level of certain amino acids may indicate the need to take additional amino acid complexes to support muscle mass and recovery after physical exertion.

1.2. Improved bioavailability and delivery systems:

An increase in the bioavailability of active substances is another important direction in the development of the BAD market. Not all substances are well absorbed in the gastrointestinal tract, so various technologies are developed that improve their absorption and delivery to target cells.

Liposomal dietary supplement: Liposomes are microscopic spherical vesicles consisting of phospholipids similar to that are part of cell membranes. Active substances enclosed in liposomes are better protected from destruction in gastric juice and penetrate more easily through cell membranes. Liposomal forms of vitamin C, turmeric, glutathione and other nutrients demonstrate higher bioavailability compared to conventional forms.
Microcapsulation: Microcapsulation is the process of covering active substances with a thin protective membrane. This allows them to protect them from the effects of light, heat, moisture and oxygen, as well as improve their solubility and digestibility. Microcapsulated probiotics, enzymes and antioxidants retain their activity for a longer time and are better tolerated.
Nanemulsion: Nanemulsions are oil dispersion in water or water in oil consisting of very small drops (from 20 to 200 nm). Due to the small size of the particles, the nanemulsii have high stability and an improved ability to penetrate through biological barriers. Nanemulsions are used to deliver fat -soluble vitamins, Q10 coenzyme and other substances that are poorly soluble in water.
Phytosomes: Phytosomes are complexes of plant extracts with phospholipids. Phospholipids improve the solubility of phytoexostracs in fats and facilitate their penetration through cell membranes. The phytosomal forms of milk thistle (silimarin), green tea (epallocatechin Gallat) and ginkgo biloba (ginkholides and bilobalides) have higher bioavailability and effectiveness compared to conventional extracts.

1.3. New sources of active substances:

The search for new sources of active substances is another important trend in the dietary supplement market. Researchers pay attention to traditional medicinal plants, seaweed, mushrooms and other natural resources with unique properties.

New generation adaptogens: Adaptogens are substances that increase the body’s resistance to various stress factors. In addition to well -known adaptogens, such as ginseng, Rodiola Pink and Eleutherococcus, new adaptogens appear that have more pronounced antioxidant, immunomodulating and neuroprotective properties. These include extracts of Reishi mushrooms, Shiytake, Metake, as well as extracts of Bacopa Monier and Ashvaganda.
Sea ingredients: The sea is a richest source of biologically active substances. Omega-3 fatty acids, fucoidan, astaxantin, collagen and other valuable nuts are obtained from seaweed, fish and other marine organisms. Particular attention is paid to the study of the properties of marine peptides and polysaccharides, which have antioxidant, anti -inflammatory and immunomodulating properties.
Exosomes from plant sources: Exosomas are microscopic vesiculas secreted by cells containing various biologically active molecules (proteins, RNA, lipids). Studies show that exosomes from plant sources, such as fruits and vegetables, can have a beneficial effect on human health. They are used to deliver nutrients and regulatory molecules to target cells.

1.4. Synergetic combinations and complex formulas:

The development of complex formulas containing synergetically interacting ingredients is another important trend in the dietary supplement market. The combination of several substances with different action mechanisms may turn out to be more effective than taking each substance separately.

Nutrichticutical complexes to support immunity: These complexes contain vitamins (C, D, E), minerals (zinc, selenium, copper), antioxidants (quercetin, resveratrol) and plant extracts (echinacea, elderberry), which enhance each other, supporting the immune system and increasing the body’s resistance to infections.
Complexes for brain health and cognitive functions: These complexes contain nootropes (Bakop Monnier, Ginkgo Biloba, Gotu Kola), antioxidants (alpha-lipoic acid, Q10 coenzyme), omega-3 fatty acids and vitamins of group B, which improve blood circulation, protect nerve cells from damage and support cognitive functions, such as memory, attention and concentration.
Joint health complexes: These complexes contain glucosamine, chondroitin, MSM (methyl sulfonylomethane), hyaluronic acid and plant extracts (turmeric, boswells), which maintain cartilage tissue health, reduce inflammation and improve joint mobility.

Section 2: New components of dietary supplements: Focus on recent research

In recent years, many new ingredients have appeared that are actively studied and included in the composition of dietary supplements. They have unique properties and can have a beneficial effect on various aspects of health.

2.1. Postbiotics:

Postbiotics are metabolites secreted by probiotics in the process of fermentation. They include short -chain fatty acids (KCHK), vitamins, enzymes, peptides and other substances. Unlike probiotics, postbiotics do not contain living microorganisms and are not at risk of transmitting resistance to antibiotics. They have a wide range of biological activity, including:

Support for intestinal health: KCZHK (butyrate, propionate, acetate) are the main source of energy for intestinal epithelial cells, support the integrity of the intestinal barrier and reduce inflammation.
Immunomodulatory action: Postbiotics stimulate the production of antimicrobial peptides and cytokines that regulate the immune response.
Antioxidant activity: Some postbiotics have antioxidant properties and protect the cells from damage caused by free radicals.
Metabolic health: Postbiotics can improve insulin sensitivity, reduce cholesterol and maintain healthy weight.

2.2. Urolitin A:

Urolitin A is a metabolite that forms in the intestines after the use of grenades, berries and nuts containing ellagannins. It has powerful antioxidant and anti -inflammatory properties. The most important mechanism for the action of urolithin A is the activation of mitophagy – the process of removing damaged mitochondria from cells. Mitochondrial dysfunction plays a key role in the development of many age diseases, such as sarcopenia (muscle loss), Alzheimer’s disease and Parkinson’s disease.

Muscle support: Urolitin A stimulates the growth of muscle cells and improves their function, slowing down the process of sarcopenia.
Neuroprotective action: Urolitin A protects nerve cells from damage and improves cognitive functions.
Anti -inflammatory effect: Urolitin A reduces the level of inflammatory markers in the body and can be useful for diseases associated with chronic inflammation.

2.3. Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN):

NR and NMN are precursors of nicotinin adenin dynucleotide (NAD+), a coherent that plays a key role in energy metabolism, DNA reparations and the regulation of cellular aging. The NAD+ level decreases with age, which leads to a deterioration in the work of mitochondria, a decrease in energy and an increased risk of developing age diseases.

Improving the level of NAD+: NR and NMN increase the level of NAD+ in cells, improving energy metabolism and maintaining mitochondria health.
Slow down aging: Increasing the level of NAD+ is associated with increasing life expectancy and improving health in old age.
Support for cognitive functions: NR and NMN improve memory, attention and concentration.
Improving metabolic health: NR and NMN improve insulin sensitivity, reduce cholesterol and maintain healthy weight.

2.4. Pyrrolokhinolinhinone (PQ):

PQQ is a vitamin -like connection that has powerful antioxidant and neuroprotective properties. He participates in mitochondriogenesis – the process of formation of new mitochondria in cells.

Stimulation of mitochondriogenesis: PQQ increases the amount of mitochondria in cells, improving energy metabolism and increasing endurance.
Neuroprotective action: Pqq protects nerve cells from damage and improves cognitive functions.
Antioxidant activity: PQq neutralizes free radicals and protects cells from oxidative stress.
Support for the cardiovascular system: PQq improves endothelium function and reduces the risk of developing cardiovascular diseases.

2.5. African mango extract (Irvingia Gabonensis):

African mango extract is a natural ingredient obtained from the seeds of wood Irvingia Gabonensis. It has lipolytic and antioxidant properties.

Weight control: African mango extract helps to reduce weight by accelerating fat metabolism and reducing appetite.
Close -to -level decrease in cholesterol: African mango extract reduces the level of “bad” cholesterol (LDL) and increases the level of “good” cholesterol (HDL).
Regulation of blood sugar: African mango extract improves insulin sensitivity and helps maintain a stable blood sugar.

2.6. Sulforafan:

Sulforafan is an isothyocyanate found in cruciferous vegetables, such as broccoli, colored cabbage and Brussels cabbage. It has powerful antioxidant, anti -inflammatory and anti -cancer properties.

Antioxidant Protection: Sulforafan activates NRF2 – a transcription factor that regulates the expression of genes encoding antioxidant enzymes.
Anti -inflammatory action: Sulforafan reduces the level of inflammatory markers in the body.
Detoxification: Sulforafan stimulates the production of detoxification enzymes that help to remove toxins from the body.
Anti -cancer properties: Sulforafan can suppress the growth of cancer cells and prevent cancer.

2.7. Berberin:

Berberin is an alkaloid contained in various plants, such as Barberry, Smatis and Hydrastis. It has a wide range of biological activity, including:

Regulation of blood sugar: Berberin improves insulin sensitivity and reduces blood sugar, which makes it useful for type 2 diabetes.
Close -to -level decrease in cholesterol: Berberin reduces the level of “bad” cholesterol (LDL) and triglycerides.
Support for health of the cardiovascular system: Berberin improves endothelium function and reduces the risk of developing cardiovascular diseases.
Anti -inflammatory action: Berberin reduces the level of inflammatory markers in the body.
Antimicrobial properties: Berberin has antibacterial, antiviral and antifungal properties.

Section 3: Focus for Health: Application of new dietary supplements

Various new dietary supplements are aimed at solving specific health problems and maintaining the optimal functioning of the body.

3.1. Diet to maintain cognitive functions and brain health:

With age, cognitive functions, such as memory, attention and concentration, can worsen. The new dietary supplements containing nootropes, antioxidants and omega-3 fatty acids can help maintain brain health and improve cognitive functions.

Bakopa Monica: Improves memory, attention and concentration.
Ginkgo biloba: Improves blood supply to the brain and protects the nerve cells from damage.
Gotted Circle: Improves blood circulation and cognitive functions.
Phosphateidixine: Supports the structure and function of cell membranes of the brain.
Alpha-lipoic acid: An antioxidant that protects the brain from damage caused by free radicals.
Coenzim q10: Improves energy metabolism in brain cells.
Omega-3 fatty acids (DGK and EPK): Support the structure and function of the brain and improve cognitive functions.
Grebenic hedgehog (Hericium Erinaceus): Stimulates the growth of nerve cells and improves cognitive functions.

3.2. Diet to maintain intestinal health and immunity:

The intestinal health plays an important role in maintaining immunity. The new dietary supplements containing probiotics, prebiotics and postbiotics can help restore the balance of intestinal microflora, improve digestion and increase immunity.

Probiotics: Restore the balance of intestinal microflora and improve digestion.
Prebiotics: Support for the growth of beneficial bacteria in the intestines.
Postbiotics: They have an anti -inflammatory, immunomodulating and antioxidant effect.
Glutamine: Amino acid that supports the integrity of the intestinal barrier.
Curcumin: It has anti -inflammatory and antioxidant properties and supports intestinal health.
Ginger: Improves digestion and reduces inflammation in the intestines.
Zinc: Supports immune function and intestinal health.
Vitamin D: Plays an important role in the regulation of an immune response.

3.3. Diet to maintain joint health:

With age, the joints become more vulnerable to damage and inflammation. The new dietary supplements containing glucosamine, chondroitin, MSM and plant extracts can help maintain the health of cartilage tissue, reduce inflammation and improve joint mobility.

Glucosamine: Construction block of cartilage fabric.
Chondroitin: Supports elasticity and elasticity of cartilage.
MSM (methyl sulfonylmetatan): The source of the sulfur necessary for the synthesis of collagen and cartilage.
Hyaluronic acid: Lubricates the joints and improves their mobility.
Curcumin: It has anti -inflammatory and antioxidant properties and reduces joint pain.
Boswellia: Reduces inflammation in the joints.
Collagen: Supports the structure and function of cartilage.
Vitamin C: It is necessary for the synthesis of collagen.

3.4. Diet to maintain health of the cardiovascular system:

Cardiovascular diseases are one of the leading causes of mortality in the world. The new dietary supplements containing omega-3 fatty acids, Q10 coenzyme, berberin and plant extracts can help reduce the risk of developing cardiovascular diseases and support the health of the heart and blood vessels.

Omega-3 fatty acids (DGK and EPK): Reduce the level of triglycerides, improve the function of the endothelium and reduce the risk of arrhythmia.
Coenzim q10: It improves energy metabolism in the heart cells and protects them from damage caused by free radicals.
Berberin: Reduces the level of cholesterol and blood sugar and improves the function of the endothelium.
Red yeast rice: Contains Monacoline K, which reduces cholesterol.
Garlic: Reduces blood pressure and improves blood circulation.
Hawthorn: Improves heart function and reduces blood pressure.
Vitamin K2: Prevents calcium deposition in the arteries.

3.5. Diet to maintain energy and reduce fatigue:

Fatigue and low level of energy are common problems that can negatively affect the quality of life. The new dietary supplements containing adaptogens, B vitamins, Q10 coenzyme and iron can help increase energy levels and reduce fatigue.

Adaptogens (ginseng, rhodiola pink, eleutherococcus): Increase the body’s resistance to stress and improve energy metabolism.
B vitamins B: Participate in energy exchange and support the function of the nervous system.
Coenzim q10: Improves energy metabolism in cells.
Iron: It is necessary for the formation of hemoglobin, which transfers oxygen to tissues.
Magnesium: Participates in energy exchange and reduces fatigue.
L-Carnitin: Transfers fatty acids to mitochondria for energy production.

Section 4: Regulatory aspects and safety of new dietary supplements

The safety and effectiveness of new dietary supplements are the subject of close attention of regulatory organs and manufacturers. It is important to consider regulatory requirements and choose products that have undergone strict quality control.

4.1. Normative dietary supplements:

In different countries, various regulatory requirements for dietary supplements apply. As a rule, dietary supplements are not subject to the same strict test as drugs. However, they must comply with certain quality and safety standards.

Requirements for composition and marking: The dietary supplement should contain ingredients allowed for use in food or dietary supplements, and be clearly marked with the composition, dosage and method of use.
Production requirements: The production of dietary supplements must comply with the GMP standards (good manufactoring practice), which ensures the quality and safety of products.
Advertising Requirements: Advertising of dietary supplements should not contain false or misleading statements about therapeutic properties.

4.2. Safety and efficiency assessment of new dietary supplements:

Before entering the market, new dietary supplements should be assessed by safety and efficiency. Safety assessment includes an analysis of the toxicity of the ingredients and possible side effects. Evaluation of effectiveness includes clinical research to confirm the declared useful properties.

Clinical research: Clinical studies are a gold standard for assessing the effectiveness of dietary supplements. They allow you to assess the effect of dietary supplements on human health in controlled conditions.
Post -marketing monitoring: After dietary supplements to the market, post -marketing monitoring is carried out to identify possible side effects and evaluate the real product efficiency in the conditions of everyday use.

4.3. The choice of high -quality and safe dietary supplements:

When choosing dietary supplements, it is important to consider the following factors:

Reputation manufacturer: Choose a dietary supplement from famous and reliable manufacturers who have a good reputation in the market.
Certification: Pay attention to the availability of quality certificates such as GMP, NSF International, USP Verified, etc.
Composition and dosage: Carefully study the composition and dosage of dietary supplements and make sure that they meet your needs.
Consumer reviews: Read the reviews of other consumers about dietary supplements to get an idea of its effectiveness and safety.
Consultation with a doctor: Consult a doctor before taking dietary supplements, especially if you have any diseases or you take medicines.

4.4. Potential risks and side effects:

Despite the fact that dietary supplements are considered relatively safe, they can cause side effects in some people. It is important to consider possible risks and be cautioned with dietary supplements.

Allergic reactions: Some dietary supplements can cause allergic reactions.
Interaction with drugs: Bad can interact with medicines by changing their effectiveness or causing side effects.
Overdose: Reception of dietary supplements in too large doses can lead to undesirable side effects.
Poor products: Some dietary supplements may contain harmful impurities or ingredients that are not indicated on the label.

Section 5: Final considerations and development prospects

The dietary supplement market continues to develop and offer new opportunities for maintaining health and preventing diseases. However, it is important to approach the choice of dietary supplements consciously and take into account individual needs and characteristics of the body.

5.1. Integrative approach to health:

Bad should be considered as part of an integrative approach to health, including healthy nutrition, regular physical activity, sufficient sleep and stress management. Bad can be a useful addition to a healthy lifestyle, but should not replace it.

5.2. Further research and development:

Further research is needed to assess the effectiveness and safety of new dietary supplements. It is important to conduct clinical studies using large groups of patients and strict quality control.

5.3. Quality Regulation and Control:

It is necessary to strengthen the regulation and quality control of dietary supplements to protect consumers from poor -quality and unsafe products. It is important to establish uniform quality and safety standards for dietary supplements produced and sold in different countries.

5.4. Education and informing consumers:

It is necessary to increase consumer awareness of dietary supplements and provide them with reliable information about the composition, dosage, method of application, efficiency and safety of dietary supplements. It is important to teach consumers to critically evaluate information about dietary supplements and choose products that meet their needs.

5.5. Future market for Dad:

The future of the BAC market is associated with personalization, technological innovation and an integrative approach to health. It is expected that in the coming years even more new and effective dietary supplements will appear, developed taking into account individual genetic characteristics, metabolic profile and the needs of a particular person. The development of technologies for the delivery of active substances and the search for new sources of nutrients will also contribute to the growth and development of the BAD market.