A complex of vitamins for joints: an overview of effective
Chapter 1: Anatomy and joint physiology: the basis of understanding the need to support
Before delving into the consideration of vitamin complexes, it is necessary to lay the foundation – an understanding of the structure and functioning of the joints. The joints that are a binder between bones provide mobility and depreciation during movement. Their health is a key factor in an active and comfortable lifestyle.
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Joint structure: The typical joint consists of several main components:
- Joint surfaces: The ends of the bones, covered with smooth hyalin cartilage.
- Hyalin cartilage: He plays the role of the shock absorber, reducing friction between bones during movement. It consists of chondrocytes (cartilage cells) and extracellular matrix, consisting mainly of collagen and proteoglycans.
- The joint capsule: A sealed shell surrounding the joint and containing synovial fluid.
- Synovial fluid: A viscous fluid lubricating the joint surfaces, providing cartilage nutrition and reducing friction. It contains hyaluronic acid, which gives it viscosity.
- Blues: Durable fibrous structures connecting bones and provide joint stability.
- Meniski (in the knee joint): Additional cartilaginous structures that perform the role of shock absorbers and stabilizers.
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Joint functions:
- Ensuring mobility: Joints allow you to perform a variety of movements, such as bending, extension, rotation and abduction.
- Depreciation: Hyalin cartilage and synovial liquid absorb blows and vibrations, protecting the bones from damage.
- Stability support: The ligaments and muscles surrounding the joint provide its stability and prevent dislocations.
- Carthing power: The synovial fluid delivers nutrients to the cartilage that does not have its own blood supply.
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Factors affecting the health of the joints:
- Age: With age, the cartilage wears out, the synovial fluid is produced less, and the ligaments lose their elasticity.
- Injuries: Damage to the joints, such as dislocations, stretching and fractures, can lead to the development of arthrosis.
- Overweight: The increased load on the joints, especially the knee and hip, accelerates the wear of the cartilage.
- Excessive physical activity: Intensive training and repeating movements can overload the joints and lead to injuries.
- Lack of physical activity: Weak muscles do not provide sufficient support to joints, increasing the risk of injuries.
- Inal meals: The deficiency of nutrients necessary to maintain the health of cartilage and bones can contribute to the development of joint diseases.
- Genetic predisposition: Some people have a genetic tendency to develop arthrosis.
- Autoimmune diseases: Rheumatoid arthritis and other autoimmune diseases can cause inflammation and destruction of joints.
Understanding the anatomy and physiology of the joints allows us to evaluate the importance of maintaining their health and the need to take vitamin complexes aimed at strengthening cartilage, ligaments and bones.
Chapter 2: Key vitamins and minerals for joint health: Scientific justification
Maintaining joint health requires an integrated approach, including a healthy lifestyle, moderate physical activity and a balanced diet. Certain vitamins and minerals play a key role in maintaining the structure and function of articular fabrics.
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Vitamin D:
- Role: Vitamin D is necessary for the absorption of calcium, which is the main building material of the bones. He also plays an important role in maintaining the health of cartilage and reducing inflammation.
- The mechanism of action: Vitamin D promotes calcium absorption in the intestines and its deposit in the bones. It also regulates the function of chondrocytes, cartilage cells, and reduces the production of inflammatory cytokines.
- Deficiency: Vitamin D deficiency can lead to osteomination (softening of bones) and increased risk of fractures, as well as to deterioration of joints.
- Sources: Sunlight, fatty fish (salmon, tuna, sardines), egg yolks, enriched products (milk, cereals).
- Dosage: The recommended daily dose of vitamin D varies depending on the age, state of health and level of vitamin D in the blood. It is usually recommended 600-800 IU per day for adults.
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Vitamin C:
- Role: Vitamin C is a powerful antioxidant that protects the cells from damage by free radicals. It is also necessary for the synthesis of collagen, the main protein that makes up the cartilage, ligaments and bones.
- The mechanism of action: Vitamin C is involved in the hydroxylating of the hole and lysine, the amino acids necessary for the formation of the stable structure of collagen. It also neutralizes free radicals that can damage cartilage cells and cause inflammation.
- Deficiency: Vitamin C deficiency can lead to a weakening of connective tissue and increased risk of joint injuries.
- Sources: Citrus fruits (oranges, lemons, grapefruits), berries (strawberries, blueberries, raspberries), vegetables (bell pepper, broccoli, spinach).
- Dosage: The recommended daily dose of vitamin C is 75-90 mg for adults.
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Vitamin E:
- Role: Vitamin E is an antioxidant that protects the cells from damage by free radicals. It also has anti -inflammatory properties.
- The mechanism of action: Vitamin E neutralizes free radicals that can damage cartilage cells and cause inflammation. He also inhibits the production of inflammatory cytokines.
- Deficiency: Vitamin E deficiency can lead to a deterioration in joints and increased risk of inflammatory diseases.
- Sources: Vegetable oils (sunflower, olive, almond), nuts (almonds, hazelnuts), seeds (sunflower, pumpkin), green leafy vegetables (spinach, broccoli).
- Dosage: The recommended daily dose of vitamin E is 15 mg for adults.
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Vitamin K:
- Role: Vitamin K plays an important role in blood coagulation and maintaining bone health. It is necessary to activate osteocalcin, protein, which binds calcium in the bones.
- The mechanism of action: Vitamin K is involved in the carboxylation of glutamic acid in osteocalcin, which allows the protein to bind calcium and strengthen the bones.
- Deficiency: Vitamin K deficiency can lead to a decrease in bone density and increased risk of fractures.
- Sources: Green leaf vegetables (spinach, broccoli, cabbage), vegetable oils (soy, olive), some fruits (avocado, kiwi).
- Dosage: The recommended daily dose of vitamin K is 90-120 μg for adults.
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Calcium:
- Role: Calcium is the main mineral that make up the bone. It is necessary to maintain their strength and density.
- The mechanism of action: Calcium is deposited in bone tissue, strengthening it and preventing the loss of bone mass.
- Deficiency: Calcium deficiency can lead to osteoporosis (reducing bone density) and increased risk of fractures.
- Sources: Dairy products (milk, cheese, yogurt), green leafy vegetables (spinach, broccoli, cabbage), enriched products (juices, cereals).
- Dosage: The recommended daily dose of calcium is 1000-1200 mg for adults.
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Magnesium:
- Role: Magnesium is involved in more than 300 biochemical reactions in the body, including the metabolism of calcium and vitamin D. It is also necessary to maintain the health of bones and muscles.
- The mechanism of action: Magnesium regulates the transport of calcium into bone tissue and is involved in the synthesis of collagen. It also relaxes the muscles, which can help reduce joint pain.
- Deficiency: Magnesium deficiency can lead to weakening of bones and muscle seizures.
- Sources: Green leaf vegetables (spinach, broccoli, cabbage), nuts (almonds, cashews), seeds (pumpkin, sunflower), whole grain products.
- Dosage: The recommended daily dose of magnesium is 310-420 mg for adults.
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Zinc:
- Role: Zinc is necessary for the synthesis of collagen and other proteins that make up cartilage and ligaments. It also has anti -inflammatory properties.
- The mechanism of action: Zinc is involved in the activity of the enzymes necessary for the synthesis of collagen and wound healing. He also inhibits the production of inflammatory cytokines.
- Deficiency: Zinc deficiency can lead to a slowdown in the healing of wounds and deterioration of the condition of the joints.
- Sources: Meat (beef, pork, poultry), seafood (oysters, crabs), nuts (cashews, almonds), seeds (pumpkin, sunflower), whole grain products.
- Dosage: The recommended daily dose of zinc is 8-11 mg for adults.
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Selenium:
- Role: Selenium is an antioxidant that protects the cells from damage by free radicals. It is also necessary for the normal function of the thyroid gland, which plays an important role in maintaining bone health.
- The mechanism of action: Selenium is part of glutathionepexidase, an enzyme that neutralizes free radicals. It also participates in the regulation of the function of osteoblasts (cells that form the bone).
- Deficiency: Selena deficiency can lead to a deterioration in the condition of the joints and an increased risk of inflammatory diseases.
- Sources: Brazilian nuts, seafood (tuna, cod, shrimp), meat (beef, pork, bird), whole grain products.
- Dosage: The recommended daily dose of selenium is 55 mcg for adults.
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Manganese:
- Role: Manganese is necessary for the synthesis of collagen and proteoglycans, the main components of the cartilage. He also participates in bone metabolism.
- The mechanism of action: The manganese is part of glycosiltransferases, enzymes necessary for the synthesis of glycosaminoglycans, and the components of proteoglycans.
- Deficiency: Manganese deficiency can lead to a deterioration in the condition of the cartilage and a slowdown in bone growth.
- Sources: Whole grain products, nuts (almonds, hazelnuts), seeds (pumpkin, sunflower), green leafy vegetables (spinach, broccoli).
- Dosage: The recommended daily dose of manganese is 2.3 mg for men and 1.8 mg for women.
These vitamins and minerals play an important role in maintaining joint health. However, it is important to remember that taking vitamin complexes should be balanced and comply with the individual needs of the body. Before taking any additives, it is recommended to consult a doctor.
Chapter 3: Chondroprotectors: glucosamine and chondroitin – action mechanisms and effectiveness
Chondroprotectors are a group of substances that are believed to contribute to the restoration of cartilage and slow down its destruction. The most famous and widely used chondroprotectors are glucosamine and chondroitin.
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Glucosamine:
- Origin and structure: Glucosamine is an aminosahar, which is naturally produced in the body and is a building block for cartilage tissue. It is the predecessor of glycosaminoglycans, the main components of proteoglycans that form extracellular matrix cartilage. It is usually used in the form of glucosamine of sulfate or glucosamine of hydrochloride.
- The mechanism of action:
- Stimulation of the synthesis of glycosaminoglycans: Glucosamine stimulates chondrocytes (cartilage cells) to the synthesis of glycosaminoglycans, which helps to restore and strengthen cartilage tissue.
- Reduced inflammation: Glucosamine has anti-inflammatory properties and can reduce the production of inflammatory cytokines, such as Interleukin-1 (IL-1).
- Carriage protection from destruction: Glucosamine can protect the cartilage from destruction by enzymes, such as metalloproteinase (MMPS).
- Output forms: Glucosamine is available in various forms, including capsules, tablets, powders and liquids.
- Dosage: It is usually recommended to take 1,500 mg of glucosamine per day, divided into several tricks.
- Side effects: Glucosamine is usually well tolerated, but in some cases side effects can occur, such as nausea, heartburn, diarrhea or constipation.
- Contraindications: Glucosamine is not recommended for people with allergies to seafood (if glucosamine is obtained from crustacean shells), as well as people with diabetes (caution and control of blood sugar are required).
- Clinical research: The results of clinical studies of glucosamine effectiveness in osteoarthritis are contradictory. Some studies show that glucosamine can reduce pain and improve joint function, while other studies have not revealed a significant effect. It is important to note that the effectiveness of glucosamine may depend on the severity of the disease and individual characteristics of the body.
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Chondroitin:
- Origin and structure: Chondroitin is glycosaminoglycan, which is also naturally contained in cartilage. It is an important component of the extracellular matrix of the cartilage and ensures its elasticity and elasticity. It is usually used in the form of chondroitin sulfate.
- The mechanism of action:
- Holding water in cartilage: Chondroitin has the ability to hold water in cartilage, which ensures its depreciation properties and stress resistance.
- Stimulation of the synthesis of proteoglycans: Chondroitin stimulates chondrocytes to the synthesis of proteoglycans, which helps to restore and strengthen cartilage.
- Reducing the activity of enzymes destroying cartilage: Chondroitin can inhibit the activity of enzymes, such as hyaluronidase and metal proproteinase (MMPS), which destroy cartilage.
- Anti -inflammatory effect: Chondroitin has anti -inflammatory properties and can reduce the production of inflammatory cytokines.
- Output forms: Chondroitin is available in various forms, including capsules, tablets, powders and liquids.
- Dosage: It is usually recommended to take 800-1200 mg of chondroitin per day, divided into several tricks.
- Side effects: Chondroitin is usually well tolerated, but in some cases side effects can occur, such as nausea, heartburn, diarrhea or constipation.
- Contraindications: Chondroitin is not recommended for people with blood coagulation, as well as pregnant and lactating women (due to the lack of sufficient safety data).
- Clinical research: As in the case of glucosamine, the results of clinical studies of the effectiveness of chondroitin in osteoarthritis are contradictory. Some studies show that chondroitin can reduce pain and improve joint function, while other studies have not revealed a significant effect. It is important to note that the effectiveness of chondroitin can depend on the severity of the disease, product quality and individual characteristics of the body.
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Combination of glucosamine and chondroitin:
- Synergetic effect: It is believed that a combination of glucosamine and chondroitin can have a more pronounced effect than the use of each of these substances separately. It is assumed that glucosamine stimulates the synthesis of glycosaminoglycans, and chondroitin ensures their retention in cartilage.
- Clinical research: Some studies have shown that a combination of glucosamine and chondroitin can be effective for reducing pain and improving joint function in people with osteoarthritis. However, other studies have not confirmed these results.
- Recommendations: Before taking glucosamine and chondroitin, it is recommended to consult a doctor, especially if you have any chronic diseases or you take other drugs.
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The importance of the quality of the product:
- Checking for compliance with standards: It is important to choose products containing glucosamine and chondroitin, which have undergone a check for compliance with quality standards and contain the declared amount of active substances.
- Certification: Pay attention to the availability of quality certificates from independent organizations, such as NSF International or USP Verified.
- Sources of origin: Find out what sources glucosamine and chondroitin are obtained from (for example, from cancerous or from cartoon cartilage).
Chondroprotectors, such as glucosamine and chondroitin, can be useful for maintaining joint health and slowing the progression of osteoarthritis. However, their effectiveness can vary depending on the individual characteristics of the body and the severity of the disease. Before taking chondroprotectors, it is recommended to consult a doctor.
Chapter 4: Other useful components in the joints for joints: MSM, collagen, hyaluronic acid
In addition to vitamins, minerals, glucosamine and chondroitin, other useful components are often included in the joints for joints, such as methyl sulfonylomethane (MSM), collagen and hyaluronic acid. These substances can also have a positive effect on joint health and improve their function.
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Methylsulfonylmetan (MSM):
- Origin and structure: MSM is an organic sulfur -containing compound that is naturally contained in plants, animals and humans.
- The mechanism of action:
- Source Source: MSM is a source of sulfur, which is necessary for the synthesis of collagen and glycosaminoglycans, the main components of cartilage.
- Anti -inflammatory effect: MSM has anti -inflammatory properties and can reduce the production of inflammatory cytokines.
- Antioxidant effect: MSM is an antioxidant and can protect the cells from damage by free radicals.
- Anesthetic effect: MSM can have an analgesic effect and reduce joint pain.
- Output forms: MSM is available in the form of powders, capsules and tablets.
- Dosage: It is usually recommended to take 1500-3000 mg MSM per day, divided into several tricks.
- Side effects: MSM is usually well tolerated, but in some cases side effects can occur, such as nausea, diarrhea or headache.
- Clinical research: Some studies have shown that MSM can reduce pain and improve joint function in people with osteoarthritis.
- A combination with glucosamine and chondroitin: MSM is often combined with glucosamine and chondroitin in the joints for joints, as it is believed that these substances can have a synergistic effect.
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Collagen:
- Origin and structure: Collagen is the main structural protein, which forms the basis of connective tissue in the body, including cartilage, ligaments, tendons and bones. There are several types of collagen, but the most common are the types of I, II and III. Type II collagen is the main component of cartilage.
- The mechanism of action:
- Building material for cartilage: Collagen is a building material for cartilage and provides its strength and elasticity.
- Collagen synthesis stimulation: Reception of collagen can stimulate chondrocytes to the synthesis of its own collagen.
- Reducing inflammation: Collagen can have anti -inflammatory properties and reduce the production of inflammatory cytokines.
- Improving cartilage hydration: Collagen can improve cartilage hydration and maintain its depreciation properties.
- Output forms: Collagen is available in various forms, including powders, capsules, tablets and liquids. The most common forms are hydrolyzed collagen (collagen peptides) and non -neaturated collagen type II.
- Hydrolyzed collagen: This is a collagen that was split into smaller peptides, which facilitates its absorption in the body.
- Non -unathed collagen type II: This is a collagen that retains its natural structure. It is believed that it can have a more pronounced effect on the immune system and reduce inflammation in the joints.
- Dosage: The recommended collagen dosage varies depending on the type of collagen and manufacturer. It is usually recommended to take 5-10 grams of hydrolyzed collagen per day or 40 mg of non-reinatted collagen type II per day.
- Side effects: Collagen is usually well tolerated, but in some cases side effects can occur, such as nausea, heartburn or diarrhea.
- Clinical research: Some studies have shown that collagen intake can reduce pain, improve joint function and increase bone density in people with osteoarthritis and osteoporosis.
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Hyaluronic acid:
- Origin and structure: Hyaluronic acid is a polysaccharide that is naturally contained in the skin, joints and other tissues of the body. It is the main component of the synovial fluid, which lubricates the articular surfaces and provides their mobility.
- The mechanism of action:
- Improving the viscosity of synovial fluid: Hyaluronic acid has high viscosity and helps to improve the viscosity of the synovial fluid, which reduces friction between the joint surfaces and facilitates movement.
- Moisturization of cartilage: Hyaluronic acid can retain water in cartilage, which provides its depreciation properties and stress resistance.
- Reduced inflammation: Hyaluronic acid can have anti -inflammatory properties and reduce the production of inflammatory cytokines.
- Collagen synthesis stimulation: Hyaluronic acid can stimulate chondrocytes to collagen synthesis.
- Output forms: Hyaluronic acid is available in various forms, including capsules, tablets, liquids and injections.
- October reception: With oral administration, hyaluronic acid can have a systemic effect on the body and improve the condition of the joints, skin and other tissues.
- Injections: Hyaluronic acid injections are administered directly into the articular cavity. This method can be effective for reducing pain and improving joint function with osteoarthritis.
- Dosage: The recommended dosage of hyaluronic acid varies depending on the form of release and manufacturer. It is usually recommended to take 100-200 mg of hyaluronic acid per day as orally or conduct a course of hyaluronic acid injections under the supervision of a doctor.
- Side effects: Hyaluronic acid is usually well tolerated, but in some cases side effects can occur, such as nausea, diarrhea or allergic reactions.
- Clinical research: Some studies have shown that taking hyaluronic acid can reduce pain and improve joint function in people with osteoarthritis. Injections of hyaluronic acid also showed their effectiveness in the treatment of osteoarthritis.
MSM, collagen and hyaluronic acid are useful components in the joints for joints. They can have a positive effect on the health of the joints, reduce pain, improve the function and slow down the progression of osteoarthritis. Before taking the joints for joints, it is recommended to consult a doctor.
Chapter 5: Choice of a complex of vitamins for joints: what to pay attention to
The choice of a suitable complex of vitamins for joints is a task that requires an attentive approach. A wide range of products presented on the market can confuse. It is necessary to take into account several key factors to make a reasonable and effective choice.
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Composition:
- The presence of the main components: Make sure that the complex includes the main components necessary for maintaining the health of the joints, such as vitamins (D, C, E, K), minerals (calcium, magnesium, zinc, selenium, manganese), glucosamine, chondroitin, MSM, collagen and hyaluronic acid.
- Concentration of active substances: Pay attention to the concentration of active substances in each portion of the complex. It should correspond to the recommended dosages to achieve the desired effect.
- The combination of components: Choose complexes in which the components are selected in such a way that they enhance each other’s action (synergistic effect). For example, a combination of glucosamine, chondroitin and MSM can be more effective than using each of these substances separately.
- Additional components: Some complexes may contain additional useful components, such as extracts of medicinal plants (for example, turmeric, ginger, bosvel), which have anti -inflammatory and analgesic properties.
- Lack of harmful additives: Avoid complexes containing artificial dyes, flavors, preservatives and other harmful additives.
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Output form:
- Capsules: Capsules are easy to swallow, they have no taste and smell, which can be important for people with a sensitive taste.
- Tablets: Tablets usually cost cheaper than capsules, but they can be more difficult to swallow.
- Powders: Powers can be mixed with water or other drinks. They can be convenient for people who experience difficulties with swallowing capsules or tablets.
- Liquids: The liquids are easily absorbed by the body, but they can have a specific taste and smell.
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Manufacturer:
- Reputation manufacturer: Choose vitamins for joints from famous and reliable manufacturers who have a good reputation in the market.
- Certification: Pay attention to the availability of quality certificates from independent organizations, such as NSF International or USP Verified. This guarantees that the product has passed the verification for compliance with quality standards and contains the declared amount of active substances.
- Customer reviews: Read customer reviews about the product to learn about their experience.
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Individual needs:
- Age: With age, the need for certain vitamins and minerals may change.
- Health status: If you have any chronic diseases, such as diabetes or liver disease, you need to consult a doctor before taking any additives.
- Allergies: Make sure that you do not have an allergy to any components that make up the complex.
- Taken medicines: If you take any medicine, consult a doctor to make sure that they do not interact with the components of a complex of vitamins for the joints.
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Price:
- The ratio of price and quality: Do not choose the cheapest complex, as it can be of poor quality. However, the high price does not always guarantee high quality. It is important to find the optimal price ratio.
- Reference: Compare the prices of different complexes of vitamins for the joints to choose the most profitable offer.
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Consultation with a doctor:
- Definition of necessity: Before taking any vitamin complexes, it is recommended to consult a doctor to determine whether you really need these additives.
- Selection of the optimal complex: The doctor can help you choose the optimal complex of vitamins for the joints, taking into account your individual needs and health status.
- Health control: The doctor can control your health status during the use of vitamin complexes to make sure that they do not have a negative effect on the body.
A thorough analysis of the composition, form of release, manufacturer, accounting for individual needs and consultation with a doctor is the key to the correct choice of a complex of vitamins for joints that help maintain their health and improve the quality of life.
Chapter 6: Alternative approaches to supporting joints: nutrition, physical activity, physiotherapy
Vitamin complexes play an important role in maintaining the health of the joints, but they are not the only way to take care of them. A comprehensive approach, including a balanced diet, regular physical activity and physiotherapy, can significantly improve the condition of the joints and prevent the development of diseases.
- Balanced nutrition:
- Anti -inflammatory diet: Nutrition, rich in antioxidants and anti -inflammatory substances, can help reduce inflammation in the joints and relieve pain.
- Fruits and vegetables: Use a large number of fruits and vegetables, especially those that are rich in vitamin C, vitamin E and antioxidants, such as berries, citrus fruits, broccoli, spinach and bell pepper.
- Fat fish: Include fatty fish in your diet, such as salmon, tuna and sardines, which is rich in omega-3 fatty acids. Omega-3 fatty acids have anti-inflammatory properties and can help reduce joint pain.
- Nuts and seeds: Use nuts and seeds, such as almonds, walnuts, linseed seeds and chia seeds, which are also rich in omega-3 fatty acids and antioxidants.
- Olive oil: Use olive oil of the first
- Anti -inflammatory diet: Nutrition, rich in antioxidants and anti -inflammatory substances, can help reduce inflammation in the joints and relieve pain.